Thermo Fisher Scientific ERK2 Monoclonal Antibody (3G1)
Rabbit monoclonal antibody (clone 3G1) specific for human ERK2, validated for WB, IHC(P), and ICC/IF. Recognizes C-terminal region of ERK2. Supplied unconjugated in liquid form at 1 mg/mL. Suitable for MAPK pathway research applications.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50 |
| Immunocytochemistry (ICC/IF) | 1:200 |
Product Specifications
| Property | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 3G1 |
| Immunogen | Recombinant human ERK2 protein, around C-terminal 150 amino acids |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
Target Information
MAPK1 (ERK2) is a serine/threonine kinase that acts as an important activator of p90 RSK, MSK, ELK1, and Stat3, and is involved in the MAPK pathway.
MAP kinases, also known as extracellular signal-regulated kinases (ERKs), serve as integration points for multiple biochemical signals and participate in various cellular processes such as proliferation, differentiation, transcription regulation, and development.
Activation of this kinase requires phosphorylation by upstream kinases. Upon activation, ERK2 translocates to the nucleus of stimulated cells, where it phosphorylates nuclear targets.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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