Thermo Fisher Scientific PGC1 alpha/beta Recombinant Rabbit Monoclonal Antibody (ARC0153)
PGC1 alpha/beta 단백질을 인식하는 Thermo Fisher의 재조합 토끼 단클론 항체. Western blot 및 ELISA에 적합하며, 인간, 마우스, 랫트 시료에 반응. 고순도의 액상 항체로, -20°C에서 안정적으로 보관 가능. 연구용 전용 제품.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:6,000 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host/Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | ARC0153 |
| Immunogen | A synthetic peptide corresponding to amino acids 699–798 of human PGC1 alpha/beta (NP_0373931) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 0.05% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2897868 |
Product Specific Information
- Positive Samples: Mouse liver, Rat heart
- Immunogen sequence:
VFGEIEECTV NLRDDGDSYG FITYRYTCDA FAALENGYTL RRSNETDFEL YFCGRKQFFK
SNYADLDSNS DDFDPASTKS KYDSLDFDSL LKEAQRSLRR
Target Information
PGC-1 beta is a tissue-specific co-activator that enhances the activity of estrogen receptor alpha.
Its co-activation function relies on a bipartite transcriptional activation domain and two LXXLL motifs that interact with the AR2 domain of ER-alpha in an estrogen-dependent manner.
Ectopic expression of this protein increases mitochondrial number and basal oxygen consumption.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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