Thermo Fisher Scientific Proteolipid Protein/Myelin PLP Monoclonal Antibody (PLP1/4259)
중추신경계의 미엘린 단백질 PLP1을 인식하는 단클론 항체. IHC(P), IHC(PFA) 등 다양한 면역조직화학 실험에 적합. Bovine, Human, Mouse, Rat 등 교차 반응성. 단백질 A/G 정제, 무보존제 PBS 용액 형태.
- 판매단위
- pk
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Assay-dependent
Immunohistochemistry (PFA fixed) (IHC (PFA))
- 1–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Bovine, Human, Mouse, Reptile, Rat |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | PLP1/4259 |
| Immunogen | Synthetic peptide GRGTKF recognizing the C-terminal region (aa272–277) of myelin proteolipid protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
PLP1 is a transmembrane proteolipid protein that is the predominant myelin protein present in the central nervous system. It plays a role in the compaction, stabilization, and maintenance of myelin sheaths, as well as in oligodendrocyte development and axonal survival.
Mutations in this gene cause X-linked Pelizaeus-Merzbacher disease and spastic paraplegia type 2.
Alternatively spliced transcript variants encoding distinct isoforms or having different 5′ UTRs have been identified for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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