Thermo Fisher Scientific DUT Recombinant Rabbit Monoclonal Antibody (6B7N2)
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카탈로그 번호 | CAS 번호 | 설명 | 상태 | 재고 | 단위 | 판매가 | 할인가 | 가격(VAT포함) | 수량 / 장바구니 / 찜 |
MA555434 | - | Thermo Fisher Scientific MA555434 DUT Recombinant Rabbit Monoclonal Antibody (6B7N2) 100 ul pk | 재고문의 | pk | 0원 | - | 0원 |
Applications
Tested Dilution
Publications
Western Blot (WB)
1:500-1:1,000
ELISA (ELISA)
1 µg/mL
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit / IgG
Expression System
HEK293 cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
6B7N2
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 160-252 of human DUT. if (typeof window.$mangular === undefined
|| !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{
targetFamily:
DUT,
uniProtId:
P33316-3,
ncbiNodeId:
9606,
antigenRange:
160-252,
antigenLength:
252,
antigenImageFileName:
MA5-55434_DUT_P33316-3_Rabbit.svg,
antigenImageFileNamePDP:
MA5-55434_DUT_P33316-3_Rabbit_PDP.jpeg,
sortOrder:
1}\]
; $mangular.isB2BCMGT = false
; $mangular.isEpitopesModalImageMultiSizeEnabled = true
;
View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}
Conjugate
Unconjugated Unconjugated Unconjugated
Form
Liquid
Concentration
0.8 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.3, with 0.05% BSA, 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Product Specific Information
Immunogen Sequence: IALPSGCYGR VAPRSGLAAK HFIDVGAGVI DEDYRGNVGV VLFNFGKEKF EVKKGDRIAQ LICERIFYPE IEEVQALDDT ERGSGGFGST GKN
Target Information
This gene encodes an essential enzyme of nucleotide metabolism. The encoded protein forms a ubiquitous, homotetrameric enzyme that hydrolyzes dUTP to dUMP and pyrophosphate. This reaction serves two cellular purposes: providing a precursor (dUMP) for the synthesis of thymine nucleotides needed for DNA replication, and limiting intracellular pools of dUTP. Elevated levels of dUTP lead to increased incorporation of uracil into DNA, which induces extensive excision repair mediated by uracil glycosylase. This repair process, resulting in the removal and reincorporation of dUTP, is self-defeating and leads to DNA fragmentation and cell death. Alternative splicing of this gene leads to different isoforms that localize to either the mitochondrion or nucleus. A related pseudogene is located on chromosome 19.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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