Thermo Fisher Scientific LZTR1 Polyclonal Antibody
LZTR1 단백질을 인식하는 Rabbit Polyclonal 항체로 Western blot 및 IHC에 적합. Human, Mouse, Rat 반응성. 항원 친화 크로마토그래피로 정제된 액상 항체. PBS buffer, 0.02% sodium azide 함유. 냉장(2–8°C) 보관 권장.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–2 µg/mL |
| Immunohistochemistry (IHC) | 5 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A 14 amino acid peptide near the amino terminus of human LZTR1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage Conditions | Maintain refrigerated at 2–8°C for up to 3 months. For long-term storage, store at −20°C. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_11153342 |
Product Specific Information
- Suggested positive control: human heart tissue lysate
- PA5-20902 can be used with blocking peptide PEP-1016
Target Information
LZTR1, a member of the BTB-kelch superfamily, was initially described as a putative transcriptional regulator based on weak homology to members of the basic leucine zipper-like family. The encoded protein localizes exclusively to the Golgi network, where it may help stabilize the Golgi complex.
Deletion of this gene may be associated with DiGeorge syndrome, a developmental defect involving the third and fourth pharyngeal pouches, leading to absence of thymus and parathyroid glands, congenital cardiac abnormalities, and facial dysmorphism.
LZTR1 is tyrosine phosphorylated and subsequently degraded upon induction of apoptosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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