Thermo Fisher Scientific Phospho-CENPA (Ser7) Polyclonal Antibody
인산화된 CENPA(Ser7)를 인식하는 Thermo Fisher Scientific의 폴리클로날 항체로, 인간 시료에 반응합니다. Western blot, ICC/IF, IP에 사용 가능하며, 높은 특이성과 재현성을 제공합니다. 항원 친화 크로마토그래피로 정제된 액상 형태입니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:100 |
| Immunoprecipitation (IP) | 1:25 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic phosphopeptide corresponding to residues surrounding pSer7 of human CENP-A protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 26 µg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | 0.01M HEPES, pH 7.5, with 0.15M NaCl, 100µg/mL BSA, 50% glycerol |
| Contains | No preservative |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_10987142 |
Product Specific Information
- It is not recommended to aliquot this antibody.
- This antibody is not cross-reactive with other histone proteins, including Histone H3.
Target Information
Centromeres are the differentiated chromosomal domains that specify the mitotic behavior of chromosomes. CENPA encodes a centromere protein which contains a histone H3-related histone fold domain required for targeting to the centromere.
CENPA is proposed to be a component of a modified nucleosome or nucleosome-like structure in which it replaces one or both copies of conventional histone H3 in the (H3-H4)₂ tetrameric core of the nucleosome particle.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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