Thermo Fisher Scientific TADA2L Polyclonal Antibody

Thermo Fisher Scientific TADA2L Polyclonal Antibody

Applications

• Western Blot (WB): 0.2–1 µg/mL

Product Specifications

Product Specific Information

Immunogen sequence:
RRQADIDSGL SPSIPMASNS GRRSAPPLNL TGLPGTEKLN EKEKELCQMV

• For short-term use: store at 2–8°C up to 1 week.
• For long-term storage: store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Predicted homology: Chicken 100%.

Target Information

TADA2L (transcriptional adapter 2-like), also known as TADA2A or ADA2-like protein, is a 443 amino acid nuclear protein that exists as two alternatively spliced isoforms. It is most abundantly expressed in testis but present in all tissues.
TADA2L contains one SANT domain and one SWIRM domain, and interacts with GCN5 and GR (NR3C1). Its ability to bind double-stranded DNA allows it to play a role in chromatin remodeling.
Although part of the PCAF complex, TADA2L is also a component of the ATAC complex, which has histone acetyltransferase activity on histones H3 and H4.
The gene encoding TADA2L maps to human chromosome 17q12.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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