Thermo Fisher Scientific Separase Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:200-1:2,000

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1220-1500 of human ESPL1 (NP_036423.4). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:Separase,uniProtId:Q14674-1,ncbiNodeId:9606,antigenRange:1220-1500,antigenLength:2120,antigenImageFileName:PA5-120352_Separase_Q14674-1_Rabbit.svg,antigenImageFileNamePDP:PA5-120352_Separase_Q14674-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1.34 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.01% thimerosal

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2913924

Product Specific Information

Positive test controls include: HeLa, Jurkat, Mouse spleen, Rat spleen, Rat testis. The target is usually found in the following locations: Cytoplasm, Nucleus.

Immunogen sequence: DEILAQAYTL LALEGLNQPS NESLQKVLQS GLKFVAARIP HLEPWRASLL LIWALTKLGG LSCCTTQLFA SSWGWQPPLI KSVPGSEPSK TQGQKRSGRG RQKLASAPLR LNNTSQKGLE GRGLPCTPKP PDRIRQAGPH VPFTVFEEVC PTESKPEVPQ APRVQQRVQT RLKVNFSDDS DLEDPVSAEA WLAEEPKRRG TASRGRGRAR KGLSLKTDAV VAPGSAPGNP GLNGRSRRAK KVASRHCEER RPQRASDQAR PGPEIMRTIP EEELTDNWRK M

Target Information

Caspase-like protease, which plays a central role in the chromosome segregation by cleaving the SCC1/RAD21 subunit of the cohesin complex at the onset of anaphase. During most of the cell cycle, it is inactivated by different mechanisms.

⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.