Thermo Fisher Scientific NMT2 Monoclonal Antibody (OTI1G2), TrueMAB
인간 NMT2 단백질을 인식하는 Mouse monoclonal antibody로 Western blot 검증 완료. 고순도 Affinity chromatography 정제. PBS, BSA, glycerol 포함 안정화 buffer. -20°C 보관, 반복 동결 해동 피할 것. 연구용 전용.
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Applications
- Western Blot (WB): Tested dilution 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1G2 |
| Immunogen | Full length human recombinant protein of human NMT2 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.03 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Target Information
Proteolytic degradation is critical to maintaining appropriate levels of short-lived and regulatory proteins involved in cellular metabolism, stress response, antigen presentation, and cell cycle regulation.
The ubiquitin-proteasome pathway deconstructs most cytosolic and nuclear proteins in eukaryotic cells, while others are degraded via the vacuolar pathway involving endosomes, lysosomes, and the endoplasmic reticulum.
The 26S proteasome, an ATP-dependent multisubunit complex (~2.5 MDa), consists of a 20S core and one or two 19S regulatory subunits. The 19S subunits recognize ubiquitinated proteins and mediate their unfolding and translocation into the 20S core.
Defects in this pathway are linked to diseases such as cystic fibrosis, Angelman’s syndrome, and Liddle syndrome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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