Thermo Fisher Scientific TdT/DNA Nucleotidylexotransferase (Acute Lymphoblastic Leukemia Marker) Monoclonal Antibody (DNTT/1453)
TdT 단백질을 표적하는 인간 반응성 마우스 단클론 항체로, 급성 림프모구성 백혈병(ALL) 진단 연구에 사용. IHC 및 ELISA에 적합하며, Protein A/G로 정제된 액상 형태. PBS 버퍼에 보존제 없이 제공, -20°C 보관 권장.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Assay-dependent
Immunohistochemistry (PFA fixed) (IHC (PFA))
- 1–2 µg/mL
ELISA
- 2–4 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | DNTT/1453 |
| Immunogen | Recombinant fragment (aa 52–192) of human DNTT protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Terminal Deoxynucleotidyl Transferase (TdT) is a DNA polymerase located in the cell nucleus that catalyzes the polymerization of deoxynucleotides at the 3′ hydroxyl ends of oligo or polydeoxynucleotide initiators, functioning without a template.
TdT is considered a highly specific marker for the diagnosis and classification of acute lymphoblastic lymphoma/leukemia (ALL).
Determination of TdT expression is valuable for differentiating histologically between lymphoblastic lymphoma and Burkitt’s lymphoma.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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