Thermo Fisher Scientific ADAMTS10 Monoclonal Antibody (496708)
인간 ADAMTS10 단백질을 인식하는 Mouse IgG1 단클론 항체로, WB 및 IP에 최적화됨. 교차 반응성이 없으며, Protein A/G로 정제된 동결건조 형태. 연구용으로 사용, -20°C에서 보관.
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Applications
Western Blot (WB)
- Tested Dilution: 1 µg/mL
Immunoprecipitation (IP)
- Tested Dilution: 25 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 496708 |
| Immunogen | CHO-derived recombinant human ADAMTS10 (Phe26–Gly1102) |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 0.5 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS with 5% trehalose |
| Contains | No Preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2605439 |
Product Specific Information
- In direct ELISAs, no cross-reactivity with recombinant human ADAMTS1, 3, 4, 5, 12, 13, 15, 16, or L2 is observed.
- Reconstitute at 0.5 mg/mL in sterile PBS.
Target Information
ADAMTS (a disintegrin and metalloproteinase domain with Thrombospondin type-1 modules) is a family of zinc-dependent proteases involved in various normal and pathological processes, including arthritis and cancer.
These enzymes participate in extracellular matrix breakdown and remodeling during embryogenesis, inflammation, tumor invasion, and metastasis.
ADAMTS proteins feature an amino-terminal propeptide domain, a metalloproteinase domain, a disintegrin-like domain, and a carboxy-terminal region with thrombospondin type-1 (TSP-1) motifs.
ADAMTS genes are mainly expressed in fetal lung, kidney, and liver tissues.
Human ADAMTS10 maps to chromosome 19p13.3, and ADAMTS19 maps to chromosome 5q31.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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