Thermo Fisher Scientific MRG15 Polyclonal Antibody
MRG15 단백질을 인식하는 Thermo Fisher Scientific의 Polyclonal 항체로, WB 및 IHC(P) 실험에 사용 가능. Human, Mouse, Pig, Rat에 반응하며 0.5 mg/mL 농도의 액상 형태로 제공. TBS buffer에 0.5% BSA 포함, -20°C에서 보관.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.1–0.3 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 4–6 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Pig, Rat |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide sequence (APKQDPKPKFQEG) corresponding to the N-terminus amino acids of MORF4L1 (aa 2–14) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_10990049 |
Product Specific Information
- Predicted to react with bovine, human, porcine, and rat based on sequence homology.
- Tested in Peptide ELISA: antibody detection limit dilution 1:128,000.
Target Information
MRG15 is a component of the NuA4 histone acetyltransferase (HAT) complex, which is involved in transcriptional activation of select genes primarily through acetylation of nucleosomal histone H4 and H2A.
This modification may alter nucleosome-DNA interactions and promote interaction of modified histones with proteins that positively regulate transcription.
The complex may be required for activation of transcriptional programs associated with oncogene and proto-oncogene-mediated growth induction, tumor suppressor-mediated growth arrest, replicative senescence, apoptosis, and DNA repair.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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