Thermo Fisher Scientific CBX8 Polyclonal Antibody
Rabbit polyclonal antibody targeting human CBX8 (residues 350–389). Validated for WB, IP, and ChIP-Seq. Supplied as unconjugated liquid form at 1 mg/mL. Recommended storage at 4°C and suitable for mouse cross-reactivity prediction.
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Thermo Fisher Scientific CBX8 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000–1:10,000 |
| Immunoprecipitation (IP) | 2–10 µg/mg lysate |
| ChIP-sequencing (ChIP-Seq) | 1–2 µg |
Product Specifications
| Specification | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 350 and the C-terminus (residue 389) of human Chromobox homolog 8 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- Based on 100% sequence identity, this antibody is predicted to react with Mouse
Target Information
CBX8 is a component of a Polycomb group (PcG) multiprotein PRC1-like complex, which maintains transcriptional repression of genes such as Hox during development.
The PRC1 complex acts through chromatin remodeling and histone modification, mediating monoubiquitination of histone H2A (Lys-119), resulting in heritable changes in chromatin expressibility.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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(이미지 파일명: A300-882A-M_CBX8_Q9HC52-1_Rabbit.svg / A300-882A-M_CBX8_Q9HC52-1_Rabbit_PDP.jpeg)
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