Thermo Fisher Scientific Kallikrein 8 Monoclonal Antibody (369910)

Applications

Tested Dilution

Publications

Immunoprecipitation (IP)

25 µg/mL

-

Neutralization (Neu)

0.7 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rat / IgG1

Class

Monoclonal

Type

Antibody

Clone

369910

Immunogen

Mouse myeloma cell line NS0-derived recombinant human Kallikrein 8/Neuropsin Gln29-Gly260 (predicted) if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:Kallikrein 8,uniProtId:O60259-1,ncbiNodeId:9606,antigenRange:29-260,antigenLength:260,antigenImageFileName:MA5-24112_Kallikrein_8_O60259-1_Rat.svg,antigenImageFileNamePDP:MA5-24112_Kallikrein_8_O60259-1_Rat_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Lyophilized

Concentration

0.5 mg/mL

Purification

Protein A/G

Storage buffer

PBS with 5% trehalose

Contains

No Preservative

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2610197

Product Specific Information

In direct ELISAs, no cross-reactivity with recombinant human (rh) UPA-1, rhKallikrein 1, 2, 3, 4, 5, 7, 9, 10, 11, 12, 13, 14, 15, rhKallikrein B1, rhHGFA, rhFactor VII, rhFactor X, rhFactor XI, rhProc, or rhThrombin is observed.

Reconstitute at 0.5 mg/mL in sterile PBS.

Endoxin level is <0.10 EU per 1 µg of the antibody by the LAL method.

Target Information

Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in tandem in a gene cluster on chromosome 19. The encoded protein may be involved in proteolytic cascade in the skin and may serve as a biomarker for ovarian cancer. Alternate splicing of this gene results in multiple transcript variants encoding different isoforms.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.