Thermo Fisher Scientific Factor VII Monoclonal Antibody (5031)
인간 Factor VII를 인식하는 마우스 단클론 항체. Western blot, ELISA, RIA 등 다양한 응용에 사용 가능. 비결합형 액상 형태로 제공되며, 고농도(14.1 mg/mL)로 -20°C에서 보관. 연구용으로만 사용.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 5 µg/mL |
| ELISA | 5–10 µg/mL |
| Radioimmune Assay (RIA) | Assay-dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 5031 |
| Immunogen | Human factor VII/VIIa |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 14.1 mg/mL |
| Purification | SDS-PAGE |
| Storage Buffer | 50% water with 50% glycerol |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_1074331 |
Product Specific Information
MA1-43011 detects Factor VII in human samples.
It has been successfully used in radioimmunoassays, western blot, and ELISA applications.
This antibody was derived from human factor VII, factor VIIa, and BFPRck factor VIIa.
Target Information
Coagulation factor VII is a vitamin K-dependent protein essential for hemostasis.
It circulates in the blood in a zymogen form and is activated by factor IXa, Xa, XIIa, or thrombin through proteolysis.
Upon activation, it forms a heavy chain (catalytic domain) and a light chain (EGF-like domains) linked by a disulfide bond.
In the presence of factor III and calcium ions, activated factor VII initiates the coagulation cascade by converting factor IX to IXa and/or factor X to Xa.
Defects in F7 production can lead to coagulopathy.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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