
Thermo Fisher Scientific LOX-1 Monoclonal Antibody (331212)
인간 LOX-1 단백질을 인식하는 Mouse IgG2b 단일클론 항체로, Western blot 및 Flow cytometry에 적합. 단백질 A/G로 정제된 동결건조 형태이며 PBS+trehalose 버퍼에 보존. 인간 시료에 특이적이며 진단용이 아닌 연구용으로 사용.
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Applications
Western Blot (WB)
- Tested Dilution: 1 µg/mL
Flow Cytometry (Flow)
- Tested Dilution: 2.5 µg per million cells
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 331212 |
| Immunogen | Mouse myeloma cell line NS0-derived recombinant human LOX-1/OLR1 (Ser61–Gln273) |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 0.5 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS with 5% trehalose |
| Contains | No Preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2608275 |
Product Specific Information
- In direct ELISAs and Western blots, this antibody does not cross-react with recombinant mouse LOX-1.
- Reconstitute at 0.5 mg/mL in sterile PBS.
- Endotoxin level is <0.10 EU per 1 µg of the antibody by the LAL method.
Target Information
LOX-1 (lectin-like oxidized LDL receptor-1) is a 40–50 kDa type II membrane glycoprotein and a class E scavenger receptor expressed by endothelial cells, macrophages, activated platelets, and smooth muscle cells.
LOX-1 binds to a wide range of ligands, including oxidized LDL (oxLDL), hypochlorite-modified HDL, aged/apoptotic cells, activated platelets, and bacteria, reflecting its versatile physiological functions.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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