Thermo Fisher Scientific SLC10A7 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

-

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200

-

Immunocytochemistry (ICC/IF)

1:100-1:500

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

A synthesized peptide derived from human SLC10A7(Accession Q0GE19), corresponding to amino acid residues I237-L287. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:SLC10A7,uniProtId:Q0GE19-2,ncbiNodeId:9606,antigenRange:237-287,antigenLength:340,antigenImageFileName:PA5-115907_SLC10A7_Q0GE19-2_Rabbit.svg,antigenImageFileNamePDP:PA5-115907_SLC10A7_Q0GE19-2_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Affinity chromatography

Storage buffer

PBS with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice

RRID

AB_2900541

Product Specific Information

Antibody detects endogenous levels of total SLC10A7.

Target Information

SLC10A7 (solute carrier family 10 (sodium/bile acid cotransporter family), member 7), also known as P7, is a 358 amino acid multi-pass membrane protein belonging to the sodium:bile acid symporter family. Existing as seven alternatively spliced isoforms, SLC10A7 is expressed at high levels in liver and lung, moderate levels in placenta, kidney, spleen, and thymus, and low levels in heart, prostate, and testis. A few members of the sodium:bile acid symporter family, such as NTCP (also known as SLC10A1) and Asbt (also known as SLC10A2), are involved in maintaining enterohepatic circulation of bile acids by mediating the first step of active bile transport through membrane barriers of liver and intestine. Other family members, including SLC10A6, play an important role in the cellular delivery of specific prohormones in testis, placenta, adrenal gland and other peripheral tissues. Orphan carriers such as SLC10A7 are uncharacterized and their functions unknown.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.