Thermo Fisher Scientific Aurora C Polyclonal Antibody
Aurora C 단백질을 인식하는 고트 폴리클로날 항체로, Western blot에 적합합니다. 합성 펩타이드 기반 면역원 사용. 0.5 mg/mL 농도의 액상 형태로 제공되며, TBS 버퍼(pH 7.3, 0.5% BSA) 포함. 연구용으로만 사용 가능.
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Thermo Fisher Scientific Aurora C Polyclonal Antibody
Applications
- Western Blot (WB): Tested dilution 1–3 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide sequence (PRAVVQLGKAQP) corresponding to the N-terminus amino acids of AURKC (aa 4–16) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_10982944 |
Product Specific Information
This antibody is tested in Peptide ELISA: antibody detection limit dilution 64,000.
Target Information
AURKC (Aurora C) is a chromosomal passenger protein that forms complexes with AURKB (Aurora B) and inner centromere proteins, playing a role in organizing microtubules in relation to centrosome/spindle function during mitosis. It is overexpressed in several cancer cell lines, suggesting an involvement in oncogenic signal transduction. Studies on the temporal expression pattern and subcellular localization of Aurora kinases in mitotic cells suggest an association with mitotic structure. Aurora kinase functional influences span from G2 phase to cytokinesis and may be involved in key cell cycle events such as centrosome duplication, chromosome bi-orientation and segregation, cleavage furrow positioning, and ingression.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지: PA5-19256_Aurora_C_Q9UQB9-1_Goat.svg)
(이미지: PA5-19256_Aurora_C_Q9UQB9-1_Goat_PDP.jpeg)
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