Thermo Fisher Scientific Cystatin 8 Polyclonal Antibody

Thermo Fisher Scientific Cystatin 8 Polyclonal Antibody

Applications

• Western Blot (WB)
  Tested Dilution: 0.1–0.3 µg/mL

Product Specifications

Product Specific Information

• This antibody is predicted to react with human based on sequence homology.
• Tested in Peptide ELISA: antibody detection limit dilution 64,000.

Target Information

The cystatin superfamily is a well-established family of cysteine protease inhibitors.
All true cystatins inhibit cysteine peptidases of the papain family, such as cathepsins, while some also inhibit legumain family enzymes.

The CRES (cystatin-related epididymal spermatogenic) protein defines a new subgroup in the family 2 cystatins of the cystatin superfamily.
CRES proteins lack two of the three consensus sites necessary for cystatin inhibition of C1 cysteine proteases.
They are preferentially expressed in postmeiotic germ cells, the proximal caput epididymidis, and anterior pituitary gonadotrophs.

As a member of the CRES subfamily, Cystatin 8 is a 142 amino acid protein expressed in the proximal caput region of the epididymis, performing a specialized role during sperm development and maturation.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

제품 이미지

(이미지: PA5-19253_Cystatin_8_O60676-1_Goat.svg)
(이미지: PA5-19253_Cystatin_8_O60676-1_Goat_PDP.jpeg)