Thermo Fisher Scientific MTMR3 Polyclonal Antibody

Applications

Western Blot (WB)

• Tested Dilution: 1:500–1:2,000

ELISA

• Tested Dilution: 1 µg/mL

Product Specifications

Product Specific Information

Immunogen sequence:
KWQEHRRSLE LSSLAGPGED PLSADSLGKP TRVPGGAELS VAAGVAEGQM ENILQEATKE ESGVEEPAHR AGIEIQEGKE DPLLEKESRR KTPEASAIGL HQDPELGDAA LRSHLDMSWP LFSQGISEQQ SGLSVLLSSL QVPPRGEDSL EVPVEQFRIE EIAEGREEAV L

Target Information

This gene encodes a member of the myotubularin dual specificity protein phosphatase gene family. The encoded protein is structurally similar to myotubularin but in addition contains a FYVE domain and an N-terminal PH-GRAM domain.
The protein can self-associate and also form heteromers with another myotubularin-related protein. It binds to phosphoinositide lipids through the PH-GRAM domain and can hydrolyze phosphatidylinositol(3)-phosphate and phosphatidylinositol(3,5)-bisphosphate in vitro.
The encoded protein has been observed to have a perinuclear, possibly membrane-bound, distribution in cells, but it has also been found free in the cytoplasm. Multiple transcript variants encoding different isoforms have been found for this gene.

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.