Thermo Fisher Scientific DMN Monoclonal Antibody (4G5)
DMN 단백질을 인식하는 Mouse IgG1 monoclonal antibody로 Western blot 및 ELISA에 사용 가능. 인간 시료 반응성. 액상 형태, 무보존제, -20°C 보관. 근육 세포 내 Type-VI intermediate filament 연구용에 적합.
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Thermo Fisher Scientific DMN Monoclonal Antibody (4G5)
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 4G5 |
| Immunogen | DMN (NP_663780.1, 1466–1565 a.a.) partial recombinant protein with GST tag (MW of GST: 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Storage Buffer | Ascites |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
VSNVEAIRSR TQEAGALGVS DRGSWRDADS RNDQAVGVSF KASAGEGDQA HREQGKEQAM FDKKVQLQRM VDQRSVISDE KKVALLYLDN EEEENDGHWF
Target Information
Type-VI intermediate filament (IF) which plays an important cytoskeletal role within the muscle cell cytoskeleton.
It forms heteropolymeric IFs with desmin and/or vimentin, and interacts with cytoskeletal proteins such as alpha-dystrobrevin, dystrophin, talin-1, utrophin, and vinculin.
These interactions link IFs to adherens-type junctions, including costameres, neuromuscular junctions, and myotendinous junctions within striated muscle cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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