Thermo Fisher Scientific ICAM-3 Polyclonal Antibody
인간 ICAM-3 단백질을 인식하는 토끼 폴리클로날 항체로, 면역세포 접착 및 활성 연구에 적합함. ICC/IF 실험에 사용 가능하며, 항원 친화 크로마토그래피로 정제됨. 액상 형태로 제공되며 장기 보관 시 -20°C에서 안정적임.
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Thermo Fisher Scientific ICAM-3 Polyclonal Antibody
Applications
- Immunocytochemistry (ICC/IF)
Tested Dilution: 0.25–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human ICAM3. Recombinant protein control fragment (Product #RP-106247). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2791132 |
Product Specific Information
Immunogen sequence:
AGGSLFVNCS TDCPSSEKIA LETSLSKELV ASGMGWAAFN LSNVTGNSRI LCSVYCNGSQ IT
Target Information
CD50 (intracellular adhesion molecule 3, ICAM-3) is a transmembrane glycoprotein expressed by leukocytes, serving as a counter-receptor for the lymphocyte function-associated antigen (LFA)-1 integrin.
It mediates contact between T cells and antigen-presenting cells, regulates LFA-1 affinity for ICAM-1, and induces T cell activation and proliferation.
ICAM-3 plays a crucial role in initiating immune responses and interacts with CD209 (DC-SIGN), facilitating communication between dendritic cells and granulocytes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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