Thermo Fisher Scientific SMN1 Polyclonal Antibody

Applications

Western Blot (WB)

• Tested Dilution: 1:2,000–1:10,000

Immunoprecipitation (IP)

• Tested Dilution: 2–5 µg/mg lysate

Product Specifications

Product Specific Information

• Recommended shelf life: 1 year from date of receipt
• Based on 100% sequence identity, this antibody is predicted to react with Orangutan

Target Information

The SMN1 gene is part of a 500 kb inverted duplication on chromosome 5q13.
This region contains multiple genes and repetitive elements, making it prone to rearrangements and deletions.
The telomeric and centromeric copies encode the same protein — survival motor neuron protein.
The SMN complex catalyzes the assembly of small nuclear ribonucleoproteins, essential for spliceosome formation.
Mutations in SMN1 cause spinal muscular atrophy types 1 and 2.

For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.

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