
Thermo Fisher Scientific SMN1 Polyclonal Antibody
SMN1 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot 및 Immunoprecipitation에 적합. Human 및 Orangutan과 반응 예측. 항원 친화 크로마토그래피로 정제된 액상형 항체로 4°C 보관.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000–1:10,000
Immunoprecipitation (IP)
- Tested Dilution: 2–5 µg/mg lysate
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 244 and 294 of Human survival of motor neuron 1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | Tris citrate/phosphate, pH 7–8 |
| Contains | 0.09% sodium azide |
| Storage conditions | 4°C |
| Shipping conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- Based on 100% sequence identity, this antibody is predicted to react with Orangutan
Target Information
The SMN1 gene is part of a 500 kb inverted duplication on chromosome 5q13.
This region contains multiple genes and repetitive elements, making it prone to rearrangements and deletions.
The telomeric and centromeric copies encode the same protein — survival motor neuron protein.
The SMN complex catalyzes the assembly of small nuclear ribonucleoproteins, essential for spliceosome formation.
Mutations in SMN1 cause spinal muscular atrophy types 1 and 2.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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