Thermo Fisher Scientific Neurotrypsin Polyclonal Antibody
Rabbit polyclonal antibody targeting human Neurotrypsin. Validated for WB and IHC applications. Lyophilized form, reconstitutable in sterile water. Suitable for CNS research and neuroplasticity studies. For research use only.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:300–1:2,000 | – |
| Immunohistochemistry (IHC) | 1:300–1:2,000 | – |
| Miscellaneous PubMed (Misc) | – | View 1 publication |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / Ig |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide from aa region 570–620 of human Neurotrypsin conjugated to an immunogenic carrier protein |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not Determined |
| Storage Buffer | Whole serum |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
Specificity of this antibody: Neurotrypsin.
Target Information
Neurotrypsin is a central nervous system-expressed serine protease whose truncation or absence causes nonsyndromic mental retardation. It is prominently expressed in structures involved in the processing and storage of learned behavior and memory, such as the cerebral cortex, hippocampus, and amygdala.
Evidence suggests that neurotrypsin has multiple functions, including axonal outgrowth, maintaining neuronal plasticity, and arranging the perineuronal environment, partly in coordination with other proteases such as tissue plasminogen activator.
At least two isoforms of neurotrypsin are known to exist.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 파일명: OSN00085W-100UL_Neurotrypsin_P56730-1_Rabbit.svg, OSN00085W-100UL_Neurotrypsin_P56730-1_Rabbit_PDP.jpeg)
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