Thermo Fisher Scientific NME1 Monoclonal Antibody (1D7)
인간 NME1 단백질을 인식하는 Mouse IgG1 단일클론 항체. Western blot, IHC, ICC, ELISA, IP 등 다양한 응용에 적합. GST 태그가 포함된 재조합 항원을 면역원으로 사용. 연구용으로만 사용 가능.
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Thermo Fisher Scientific NME1 Monoclonal Antibody (1D7)
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–5 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 3 µg/mL |
| Immunocytochemistry (ICC/IF) | 10 µg/mL |
| ELISA | 0.1 ng/mL |
| Immunoprecipitation (IP) | 1–5 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 1D7 |
| Immunogen | NME1 (NP_000260, 43–152 a.a.) partial recombinant protein with GST tag (MW of GST tag: 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
ASEDLLKEHY VDLKDRPFFA GLVKYMHSGP VVAMVWEGLN VVKTGRVMLG ETNPADSKPG TIRGDFCIQV GRNIIHGSDS VESAEKEIGL WFHPEELVDY TSCAQNWIYE
Target Information
NME1 was identified because of its reduced mRNA transcript levels in highly metastatic cells. Nucleoside diphosphate kinase (NDK) exists as a hexamer composed of A (encoded by this gene) and B (encoded by NME2) isoforms. Mutations in the gene have been identified in aggressive neuroblastomas. Two transcript variants encoding different isoforms have been found for this gene. Co-transcription of this gene and the neighboring downstream gene (NME2) generates naturally occurring transcripts (NME1-NME2), which encode a fusion protein comprised of sequence sharing identity with each individual gene product.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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