Thermo Fisher Scientific CSNK1E Monoclonal Antibody (OTI5C9), TrueMAB

Applications

• Western Blot (WB)
  Tested Dilution: 1:2,000

Product Specifications

Product Specific Information

For reconstitution, add 100 µL distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).

Target Information

CSNK1E (CK1 epsilon) is a serine/threonine kinase involved in various cellular processes, including:

• Vesicular trafficking
• DNA damage repair
• Cell cycle progression
• Cytokinesis

CSNK1E phosphorylates key regulatory proteins controlling cell differentiation, proliferation, chromosome segregation, circadian rhythms, and metabolic pathways.
CK1 family members share a conserved kinase domain but differ in N- and C-terminal regions. Mammals possess seven family members: α, β, γ1, γ2, γ3, δ, and ε.
CK1ε positively regulates Akt, possibly by inhibiting PP2A, and plays an important role in neurodegenerative diseases.

For Research Use Only.
Not for use in diagnostic procedures or resale without express authorization.

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