Thermo Fisher Scientific CSNK1E Monoclonal Antibody (OTI5C9), TrueMAB
Human CSNK1E 단백질을 인식하는 Mouse monoclonal antibody (Clone OTI5C9). Western blot에 최적화된 TrueMAB 포맷. Lyophilized 형태로 제공되며, 높은 순도의 affinity chromatography 정제. 연구용으로만 사용 가능.
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- pk
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Applications
- Western Blot (WB)
Tested Dilution: 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI5C9 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 153–416 of human CSNK1E produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
CSNK1E (CK1 epsilon) is a serine/threonine kinase involved in various cellular processes, including:
- Vesicular trafficking
- DNA damage repair
- Cell cycle progression
- Cytokinesis
CSNK1E phosphorylates key regulatory proteins controlling cell differentiation, proliferation, chromosome segregation, circadian rhythms, and metabolic pathways.
CK1 family members share a conserved kinase domain but differ in N- and C-terminal regions. Mammals possess seven family members: α, β, γ1, γ2, γ3, δ, and ε.
CK1ε positively regulates Akt, possibly by inhibiting PP2A, and plays an important role in neurodegenerative diseases.
For Research Use Only.
Not for use in diagnostic procedures or resale without express authorization.
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