Thermo Fisher Scientific CD45 Monoclonal Antibody (1.11.32)
양 CD45(Leukocyte Common Antigen)를 인식하는 마우스 단클론 항체로, IHC, Flow Cytometry, IP 등 다양한 면역분석에 사용 가능. 비결합형(Unconjugated) 형태이며, 단기 4°C, 장기 -20°C 보관 권장. 연구용으로만 사용.
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Applications and Tested Dilution
| Application | Tested Dilution | Notes |
|---|---|---|
| Immunohistochemistry (Paraffin) (IHC-P) | Assay-dependent | |
| Immunohistochemistry (Frozen) (IHC-F) | Assay-dependent | |
| Flow Cytometry (Flow) | 1:25–1:200 | |
| Immunoprecipitation (IP) | Assay-dependent |
Product Specifications
| Specification | Detail |
|---|---|
| Species Reactivity | Sheep |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 1.11.32 |
| Immunogen | Ovine efferent lymphatic duct lymphocytes |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2745352 |
Available Formats
Product Specific Information
Mouse anti-Sheep CD45 antibody, clone 1.11.32, recognizes ovine CD45 (Leukocyte common antigen), expressed on all ovine lymphocytes, macrophages, and granulocytes.
Target Information
CD45 (LCA, leukocyte common antigen) is a receptor-type protein tyrosine phosphatase (PTP) expressed on all nucleated hematopoietic cells, accounting for about 10% of all surface proteins on lymphocytes. It is absent on non-hematopoietic cells and tissues. CD45 plays a key role in lymphocyte development and antigen signaling, regulating Src-family kinases and JAK kinases, and influencing cytokine receptor signaling. It also contributes to cell survival, integrin-mediated signaling, and apoptosis regulation. Multiple isoforms exist due to alternative splicing, differing in extracellular domains but sharing identical transmembrane and cytoplasmic domains.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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