Thermo Fisher Scientific RBFOX2 Polyclonal Antibody

Applications and Tested Dilution

• Western Blot (WB): 1:500–1:3,000

Product Specifications

Product Specific Information

• Recommended positive controls: HepG2, HCT116
• Predicted reactivity: Mouse (98%), Rat (96%), Xenopus laevis (80%), Pig (96%), Rhesus Monkey (96%), Bovine (96%)
• Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Target Information

This gene is one of several human genes similar to the C. elegans gene Fox-1. It encodes an RNA-binding protein that regulates alternative exon splicing in the nervous system and other cell types. The protein binds to a conserved UGCAUG element downstream of many alternatively spliced exons, promoting inclusion of the alternative exon in mature transcripts. It also interacts with the estrogen receptor 1 transcription factor and regulates its transcriptional activity. Multiple transcript variants encoding different isoforms have been identified.

Safety Information

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.