Thermo Fisher Scientific VDAC Polyclonal Antibody
Rabbit polyclonal antibody against VDAC1 for WB applications. Reacts with human, mouse, and rat. Lyophilized form, reconstitutable with DDW. High specificity via antigen affinity purification. For research use only.
- 카탈로그번호
- AVC-001-xxxxx (2개 옵션)
- 판매단위
- pk
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Applications
- Western Blot (WB): Tested dilution 1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | (C)DGKNVNAGGHK, corresponding to amino acid residues 264–274 of rat VDAC1 (Intracellular) |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 0.8 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 1% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Reconstitution: Add 50 µL or 0.2 mL double distilled water (DDW), depending on sample size.
The antibody ships as a lyophilized powder at room temperature. Upon arrival, store at -20°C.
Reconstituted solution can be stored at 4°C, protected from light, for up to 1 week.
For longer storage, aliquot and keep at -20°C. Avoid multiple freeze/thaw cycles.
Centrifuge antibody preparations before use (10,000 × g, 5 min).
Target Information
Voltage-dependent anion channel (VDAC) proteins are abundant, pore-forming proteins located in the mitochondrial outer membrane and also expressed in the plasma membrane.
At least three different VDAC genes have been identified in vertebrates.
VDAC proteins play essential roles in cellular metabolism and apoptosis.
They form major pathways for metabolite exchange (e.g., ADP/ATP, succinate, citrate) between cytosol and mitochondria.
VDAC1 in the plasma membrane may regulate apoptosis via redox activity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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