Thermo Fisher Scientific UGT1A9 Polyclonal Antibody
UGT1A9 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, Human, Mouse, Rat 시료에 반응합니다. Western blot, IHC, ELISA에 적합하며 고순도 Affinity Chromatography로 정제되었습니다. 연구용으로만 사용됩니다.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 26–250 of human UGT1A9 (NP_066307.1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.56 mg/mL |
| Purification | Affinity Chromatography |
| Storage buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | –20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Wet ice |
| RRID | AB_2914039 |
Product Specific Information
Positive test controls include: A-549, HT-29, MCF7, HeLa, Mouse liver.
The target is usually found in the following locations: Endoplasmic reticulum membrane, Microsome, Single-pass membrane protein.
Immunogen sequence:
GKLLVVPMDG SHWFTMRSVV EKLILRGHEV VVVMPEVSWQ LGRSLNCTVK TYSTSYTLED LDREFKAFAH AQWKAQVRSI YSLLMGSYND IFDLFFSNCR SLFKDKKLVE YLKESSFDAV FLDPFDNCGL IVAKYFSLPS VVFARGILCH YLEEGAQCPA PLSYVPRILL GFSDAMTFKE RVRNHIMHLE EHLLCHRFFK NALEIASEIL QTPVTEYDLY SHTSI
Target Information
UGT1A9 is a UDP-glucuronosyltransferase, an enzyme of the glucuronidation pathway that transforms small lipophilic molecules—such as steroids, bilirubin, hormones, and drugs—into water-soluble, excretable metabolites.
This gene is part of a complex locus encoding several UDP-glucuronosyltransferases, including thirteen unique alternate first exons followed by four common exons. Nine of these exons produce proteins with different N-termini and identical C-termini. Each first exon encodes the substrate binding site and is regulated by its own promoter.
The enzyme encoded by this gene is active on phenols.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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