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Thermo Fisher Scientific Phospho-p21 (Thr57) Polyclonal Antibody
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인간, 생쥐, 랫트에서 인산화된 p21(Thr57)을 특이적으로 검출하는 폴리클로날 항체. Western blot에 적합하며, 액상 형태로 제공. 1 mg/mL 농도, PBS/glycerol 버퍼에 저장. 종양 억제 단백질 p21 연구용으로 적합.
- 카탈로그번호
- PA564842
- 판매단위
- pk
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마지막 업데이트 2025. 08. 02. 오후 09:33
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Thermo Fisher Scientific PA564842 Phospho-p21 (Thr57) Polyclonal Antibody 100 ul pk판매 단위 pk ·
재고 확인 필요
631,500원VAT 포함 694,650원
Thermo Fisher Scientific · Thermo Fisher Scientific Phospho-p21 (Thr57) Polyclonal Antibody
Applications
- Western Blot (WB): Tested dilution 1:1,000
- Publications: [References not provided]
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human p21Cip1 (Phospho-Thr57) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2662837 |
Product Specific Information
Phospho-p21 (Thr57) Polyclonal Antibody detects endogenous levels of p21 only when phosphorylated at Thr57.
Target Information
Protein p21 is a tumor suppressor protein and an inhibitor of Cyclin-dependent kinases (CDK), transcriptionally activated by p53.
- Plays a key role in cellular response to genotoxic stress.
- In the nucleus, p21 binds and inhibits Cdk1 and Cdk2, blocking G1/S or G2/M transitions after DNA damage.
- In the cytoplasm, p21 exhibits anti-apoptotic effects by inhibiting caspase 3 and kinases ASK1 and JNK.
- p21 has dual roles in carcinogenesis, functioning as both a tumor suppressor and oncogene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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