Thermo Fisher Scientific West Nile Virus Core Antigen Polyclonal Antibody
West Nile Virus 핵심 단백질을 인식하는 토끼 폴리클로날 항체. WB 및 ICC/IF에 사용 가능하며, 항원 친화 크로마토그래피로 정제됨. 비결합형 액상 형태로 제공되며, 연구용으로만 사용 가능.
- 카탈로그번호
- PA520103
- 판매단위
- pk
카탈로그
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Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1 µg/mL | View 1 publication |
| Immunocytochemistry (ICC/IF) | 20 µg/mL | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Virus |
| Published Species | Virus |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide corresponding to 15 amino acids near the carboxy terminus of the West Nile Virus core protein. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage Conditions | Maintain refrigerated at 2–8°C for up to 3 months. For long-term storage, store at -20°C. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_11156179 |
Product Specific Information
PA5-20103 can be used with blocking peptide PEP-0221.
Target Information
West Nile Virus (WNV) is a member of the Flaviviridae family, which includes St. Louis encephalitis virus, yellow fever virus, and Dengue virus.
WNV was first isolated in 1937 in the West Nile region of Uganda and has since become prevalent across Africa, Asia, and Europe. It has spread rapidly throughout the United States, with cases observed in every continental state.
Virus particles consist of a dense core composed of the core/capsid protein encapsulating the RNA genome, surrounded by a membrane envelope embedded with envelope and matrix proteins. These proteins play a major role in WNV entry into target cells.
The viral core protein is believed to contribute to WNV-associated inflammation through apoptosis induced via the caspase-9 pathway, as delivery of the core gene into the striatum of mouse brain and skeletal muscle resulted in cell death and inflammation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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