Thermo Fisher Scientific TNFAIP8L1 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:1,000-1:3,000

-

Product Specifications

Species Reactivity

Human, Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Synthesized peptide derived from human TNFAIP8L1. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:TNFAIP8L1,uniProtId:Q8WVP5-1,ncbiNodeId:9606,antigenRange:42-63,antigenLength:186,antigenImageFileName:PA5-68004_TNFAIP8L1_Q8WVP5-1_Rabbit.svg,antigenImageFileNamePDP:PA5-68004_TNFAIP8L1_Q8WVP5-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

affinity chromatography

Storage buffer

PBS, pH 7.4, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice

RRID

AB_2691628

Product Specific Information

Predicted to react with Human samples.

Target Information

Tumor necrosis factor, α-induced protein 8-like 1, also known as TNFα-IP 8L1, is a 186 amino acid protein belonging to the TNFα-IP 8 family. Members of the TNFα-IP 8 family are induced by nuclear factor-κB 9 (NFκB) and tumor necrosis factor (TNF), although induction by TNF is dependent upon NFκB activation. TNFα-IP 8 proteins also act as a negative mediator of apoptosis and may play a role in tumor progression. They suppress TNF-mediated apoptosis by inhibiting caspase-8 activity but not the processing of procaspase-8, subsequently resulting in inhibition of BID cleavage and caspase-3 activation.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.