Thermo Fisher Scientific RARS Polyclonal Antibody
Thermo Fisher Scientific의 RARS Polyclonal Antibody는 인간 RARS 단백질을 인식하는 토끼 다클론 항체로, Western blot 및 ICC/IF에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, 다양한 종에서 예측 반응성을 보입니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:3,000 |
| Immunocytochemistry (ICC/IF) | 1:100–1:1,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fragment corresponding to a region within amino acids 170–458 of Human Arginyl tRNA synthetase |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | 0.1M Tris glycine, pH 7, with 20% glycerol |
| Contains | 0.01% thimerosal |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2547619 |
Product Specific Information
- Recommended positive controls: A431, H1299, HeLa, HepG2
- Predicted reactivity: Mouse (90%), Rat (90%), Pig (90%), Chicken (83%), Rhesus Monkey (97%), Chimpanzee (100%), Bovine (93%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
The fidelity of protein synthesis requires efficient discrimination of amino acid substrates by aminoacyl-tRNA synthetases.
ArgRS (Arginyl-tRNA synthetase), also known as RARS or DALRD1, belongs to the class-I aminoacyl-tRNA synthetase family that includes related proteins such as LeuRS, ValRS, and IleRS.
These enzymes catalyze the aminoacylation of tRNA by their cognate amino acid. ArgRS localizes to the cytoplasm, existing as a monomer or within a multisubunit complex.
In the presence of ATP, arginine, and tRNA, ArgRS joins Arg to tRNA(Arg) at its synthetic active site.
Two cytoplasmic forms of ArgRS have been described in mammals, differing by a 73-amino-acid sequence required for assembly into the multisubunit complex.
Safety Information
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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