Thermo Fisher Scientific PON1 Polyclonal Antibody
Thermo Fisher Scientific의 PON1 Polyclonal Antibody는 인간, 마우스, 랫트 반응성을 가진 Rabbit IgG 항체로, Western blot에 적합합니다. 합성 펩타이드(186-201aa)를 면역원으로 사용하며, 항원 친화 크로마토그래피로 정제되었습니다. 연구용으로만 사용 가능합니다.
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Applications
- Western Blot (WB): Tested dilution 0.1–0.5 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to human PON1 (186–201aa FLDPYLQSWEMYLGLA) |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 500 µg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with 5 mg BSA |
| Contains | 0.05 mg sodium azide, 0.05 mg thimerosal |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2746959 |
Product Specific Information
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
Target Information
The paraoxonase (PON) gene family in humans includes PON1, PON2, and PON3, located on chromosome 7q21.3–22.1.
PON1 is primarily synthesized in the liver and secreted into plasma, associating with HDL.
It hydrolyzes active metabolites of organophosphorus insecticides (e.g., chlorpyrifos oxon, diazoxon) and nerve agents such as sarin, soman, and VX.
PON1 polymorphism may contribute to neurodegeneration and is considered an independent risk factor for Parkinson’s disease.
⚠ WARNING
This product can expose you to chemicals including mercury, known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures.
Not for resale without express authorization.
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