Thermo Fisher Scientific ACAT2 Polyclonal Antibody
Thermo Fisher Scientific의 ACAT2 Polyclonal Antibody는 인간 ACAT2 단백질을 인식하는 토끼 유래 IgG 항체로, Western blot에 최적화되어 있습니다. 합성 펩타이드 면역원으로 제작되었으며, 액상 형태로 0.5 mg/mL 농도입니다. 연구용으로만 사용 가능합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 0.1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the N-terminal region of human ACAT2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2688566 |
Product Specific Information
This target displays homology in the following species:
- Human: 100%
Target Information
This gene represents a member of the frizzled gene family, which encodes 7-transmembrane domain proteins that act as receptors for Wnt signaling proteins.
The protein encoded by this family member contains:
- A signal peptide
- A cysteine-rich domain in the N-terminal extracellular region
- Seven transmembrane domains
Unlike other family members, this protein does not contain a C-terminal PDZ domain-binding motif.
It functions as a negative regulator of the canonical Wnt/beta-catenin signaling cascade, thereby inhibiting processes that trigger oncogenic transformation, cell proliferation, and inhibition of apoptosis.
Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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