Thermo Fisher Scientific EZH2 Monoclonal Antibody (UMAB264), UltraMAB
EZH2 단백질을 표적으로 하는 UltraMAB 단클론 항체. 인간 시료에 반응하며 IHC(P)에서 1:100 희석으로 사용 가능. 고순도 친화 크로마토그래피 정제, 안정적인 PBS/BSA/glycerol 버퍼. 연구용으로 EZH2 관련 발현 및 기능 분석에 적합.
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Applications
- Immunohistochemistry (Paraffin) (IHC (P)): Tested dilution 1:100
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | UMAB264 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 182–431 of human EZH2 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5–1.0 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Target Information
EZH2 (Histone-lysine N-methyltransferase) is a member of the Polycomb-group (PcG) family. PcG family members form multimeric protein complexes that maintain the transcriptional repressive state of genes over successive cell generations.
This protein associates with the embryonic ectoderm development protein, the VAV1 oncoprotein, and the X-linked nuclear protein. EZH2 may play a role in the hematopoietic and central nervous systems.
Mutations affecting EZH2 can cause Weaver syndrome (WVS).
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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