Thermo Fisher Scientific MiTF Polyclonal Antibody
MiTF 단백질을 인식하는 토끼 폴리클로날 항체로, 마우스 시료에 반응합니다. Western blot에 적합하며, 합성 펩타이드 면역원으로 제작되었습니다. 0.5 mg/mL 농도의 액상형 시약으로, PBS와 2% sucrose에 보관되며 -20°C에서 저장합니다.
- 카탈로그번호
- PA568948
- 판매단위
- pk
카탈로그
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Applications
Western Blot (WB)
- Tested Dilution: 0.2–1.0 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to a region of mouse MiTF (aa 228–277) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2688947 |
Product Specific Information
This target displays homology in the following species:
Cow: 93% • Dog: 93% • Guinea Pig: 100% • Horse: 100% • Human: 100% • Mouse: 100% • Rabbit: 93% • Rat: 100% • Sheep: 93%
Target Information
Mi is a basic helix-loop-helix-leucine zipper (b-HLH-ZIP) transcription factor implicated in pigmentation, mast cells, and bone development.
Mutation of Mi causes Waardenburg Syndrome type II in humans. In mice, the loss of pigmented cells in the skin, eye, and inner ear results, along with osteopetrosis and defects in natural killer and mast cells.
There are two known isoforms of Mi differing by 66 amino acids at the NH₂ terminus.
Shorter forms are expressed in melanocytes (52 kDa and 56 kDa bands), while the longer form (60–70 kDa) appears in osteoclasts, B16 melanoma cells, mast cells, and heart.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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