Thermo Fisher Scientific IDH2 Polyclonal Antibody
Rabbit polyclonal antibody targeting human IDH2 protein. Suitable for research use in studying isocitrate dehydrogenase function and metabolism. Supplied as a liquid at 0.05 mg/mL concentration. Store short-term at 4°C, long-term at -20°C. For research...
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Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human IDH2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.05 mg/mL |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2789474 |
Product Specific Information
Immunogen sequence:
REPIICKNIP RLVPGWTKPI TIGRHAHGDQ YKATDFVADR AGTFKMVFTP KDGSGVKEWE VYNFPAGGVG MGMYNTDESI SGFAHSCFQY AIQKKWPLYM STKNTILKAY DGRFKDIFQE IFDKHYKTDF D
Target Information
Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD as the electron acceptor and the other NADP.
Five isocitrate dehydrogenases have been reported: three NAD-dependent isocitrate dehydrogenases localized to the mitochondrial matrix, and two NADP-dependent isocitrate dehydrogenases, one mitochondrial and the other predominantly cytosolic.
Each NADP-dependent isozyme is a homodimer. The protein encoded by this gene is the NADP-dependent isocitrate dehydrogenase found in the mitochondria. It plays a role in intermediary metabolism and energy production, and may associate or interact with the pyruvate dehydrogenase complex.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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