Thermo Fisher Scientific Adiponectin Monoclonal Antibody (OTI7H8), TrueMAB
Adiponectin 단백질을 인식하는 마우스 단클론항체로, Western blot과 IHC(파라핀)에서 검증됨. Human 시료에 반응하며, 동결건조 형태로 제공. PBS 버퍼에 8% 트레할로스 포함, -20°C 보관. 연구용으로만 사용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI7H8 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 19–244 of human ADIPOQ produced in SF9 cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
Adiponectin is a protein hormone secreted exclusively by adipocytes that regulates lipid and glucose metabolism.
It plays a role in homeostasis and obesity, with decreased levels associated with obesity, insulin resistance, and type 2 diabetes.
In mice, adiponectin improves insulin signaling via activation of AMP kinase and PPAR-alpha, enhancing fatty acid oxidation and reducing intramyocellular lipid levels.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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