Thermo Fisher Scientific APCS Monoclonal Antibody (4F3)

Applications

Tested Dilution

Publications

Western Blot (WB)

1-5 µg/mL

-

Immunocytochemistry (ICC/IF)

20 µg/mL

-

ELISA (ELISA)

3 ng/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG2a, kappa

Class

Monoclonal

Type

Antibody

Clone

4F3

Immunogen

APCS (AAH07058.1, 35 a.a. approximately 149 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:Serum Amyloid P,uniProtId:P02743-1,ncbiNodeId:9606,antigenRange:35-149,antigenLength:223,antigenImageFileName:H00000325-M11_Serum_Amyloid_P_P02743-1_House_mouse.svg,antigenImageFileNamePDP:H00000325-M11_Serum_Amyloid_P_P02743-1_House_mouse_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

See Label

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.4

Contains

no preservative

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

Product Specific Information

Sequence of this protein is as follows: VTDHVNLITP LEKPLQNFTL CFRAYSDLSR AYSLFSYNTQ GRDNELLVYK ERVGEYSLYI GRHKVTSKVI EKFPAPVHIC VSWESSSGIA EFWINGTPLV KKGLRQGYFV EAQPK

Target Information

The protein encoded by this gene is a glycoprotein, belonging to the pentraxin family of proteins, which has a characteristic pentameric organization. These family members have considerable sequence homology which is thought to be the result of gene duplication. The binding of the encoded protein to proteins in the pathological amyloid cross-beta fold suggests its possible role as a chaperone. This protein is also thought to control the degradation of chromatin. It has been demonstrated that this protein binds to apoptotic cells at an early stage, which raises the possibility that it is involved in dealing with apoptotic cells in vivo.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.