Thermo Fisher Scientific EphB1/EphB3/EphB4 Polyclonal Antibody
EphB1/EphB3/EphB4 단백질을 인식하는 Rabbit Polyclonal 항체로, WB 및 ICC/IF에 적합합니다. 인간 EPHB1 유래 합성 펩타이드로부터 제작되었으며, 비결합(Unconjugated) 상태의 액상 포맷으로 제공됩니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human EPHB1 (Accession P54762), corresponding to amino acid residues N755–S805 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2817642 |
Product Specific Information
This antibody detects endogenous levels of total EPH B1/3/4.
Target Information
Ephrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into two classes:
- Ephrin-A (EFNA): Anchored to the membrane by a glycosylphosphatidylinositol linkage
- Ephrin-B (EFNB): Transmembrane proteins
The Eph family of receptors are divided into two groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors constitute the largest subgroup of the receptor tyrosine kinase (RTK) family. EphB4 binds to ephrin-B2 and plays an essential role in vascular development.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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