Thermo Fisher Scientific NALP12 Polyclonal Antibody
Thermo Fisher Scientific의 NALP12 Polyclonal Antibody는 Mouse에 반응하는 Goat 유래 IgG 항체로, Western Blot에 적합합니다. 염증 반응 조절 관련 연구에 활용되며, 고순도 액상 형태로 안정적인 신뢰성을 제공합니다.
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Applications
- Western Blot (WB): Tested Dilution 1–3 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide with sequence C-KPGTPTFKVPANQR |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2933738 |
Product Specific Information
This antibody is tested in Peptide ELISA with an antibody detection limit dilution of 1:128,000.
Target Information
NALP proteins are cytoplasmic proteins forming a subfamily within the larger CATERPILLER family, playing a crucial role in cell proliferation and reproduction.
NALP12 (Monarch-1) contains a C-terminal leucine-rich repeat (LRR) region, an N-terminal Pyrin domain (PYD), a NACHT domain, and a NACHT-associated domain.
NALP12 acts as an attenuating factor of inflammation by suppressing NF-kappa-B activation through TLR-signaling molecules such as MyD88, IRAK-1, TRAF6, and RIPK1 in activated monocytes.
Mutations in NALP12 are associated with hereditary periodic fever syndromes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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