
Thermo Fisher Scientific IQGAP1 Polyclonal Antibody
IQGAP1 단백질을 검출하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot 및 Immunocytochemistry에 적합하며, Human, Mouse, Rat 시료에서 반응. 고순도 Affinity chromatography 정제, 액상 형태로 안정적 보관 가능.
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Thermo Fisher Scientific IQGAP1 Polyclonal Antibody
Applications and Tested Dilution
- Western Blot (WB): 1:500–1:1,000
- Immunocytochemistry (ICC/IF): 1:100–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human IQGAP1 (Accession P46940), corresponding to amino acid residues M246–I296 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C |
| Shipping conditions | Wet ice |
| RRID | AB_2851248 |
Product Specific Information
Antibody detects endogenous levels of total IQGAP1.
Target Information
This gene encodes a member of the IQGAP family. The protein contains four IQ domains, one calponin homology domain, one Ras-GAP domain, and one WW domain.
It interacts with components of the cytoskeleton, cell adhesion molecules, and several signaling molecules to regulate cell morphology and motility.
Expression of the protein is upregulated by gene amplification in two gastric cancer cell lines.
Usage Note
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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