Thermo Fisher Scientific RASA1 Monoclonal Antibody (OTI1H2), TrueMAB
RASA1 단백질을 인식하는 Mouse IgG1 단클론 항체로, Western blot과 Immunocytochemistry에 적합. HEK293T 세포에서 생산된 인간 RASA1 전체 길이 단백질을 면역원으로 사용. 무보존제, 동결건조 형태로 제공되며, 연구용으로만 사용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunocytochemistry (ICC/IF) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1H2 |
| Immunogen | Full-length human recombinant RASA1 protein produced in HEK293T cells |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to reach a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL (Product #89882).
Target Information
TACC1 is located on the 8p11 chromosomal region, amplified in about 15% of breast tumor samples. The short arm of chromosome 8 also contains FGFR1, which is overexpressed in many breast cancers.
TACC family members (TACC1, TACC2, TACC3) are closely mapped to FGFR genes (FGFR1, FGFR2, FGFR3) on chromosomes 4, 8, and 10, suggesting similar roles in cell growth and differentiation.
TACC1 contains a conserved C-terminal region similar to the Drosophila homolog D-TACC, which is necessary for normal spindle function. Mammalian TACC proteins interact with centrosomes and microtubules in a similar manner.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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