Thermo Fisher Scientific GPR77 (extracellular) Polyclonal Antibody
Rabbit polyclonal antibody targeting extracellular GPR77 (C5AR2) for WB application. Lyophilized form, 0.85 mg/mL concentration, stored at -20°C. Recognizes residues 4–18 of human C5a receptor 2. For research use only.
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Applications
Western Blot (WB)
- Tested Dilution: 1:400
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide (C)DSVSYEYGDYSDLSD, corresponding to amino acid residues 4–18 of human C5a Anaphylatoxin Chemotactic Receptor 2 |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 0.85 mg/mL |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2735880 |
Product Specific Information
Product is shipped at room temperature as a lyophilized powder and should be stored at -20°C upon receipt.
Reconstitution: add 50 µL of deionized water.
Target Information
C5AR2 is an orphan member of the anaphylatoxin receptor family. It is a seven-transmembrane G-protein-coupled receptor with an N-terminal N-glycosylation site, conserved cysteines, and potential C-terminal phosphorylation sites.
It binds to C5a and C5a-des-Arg and functions as a scavenger receptor that negatively modulates C5aR-mediated inflammation.
Northern Blot analysis indicates co-expression with C5aR in tissues such as neutrophils, macrophages, mast cells, dendritic cells, brain, lung, heart, kidney, liver, ovary, and testis.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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