
ELK Biotechnology RIN2 rabbit pAb
RIN2 단백질을 인식하는 토끼 다클론 항체로, WB 및 ELISA에 적합합니다. 인간 및 생쥐 시료에 반응하며, 세포질 내 RIN2 단백질 검출에 사용됩니다. 고순도 IgG 형식으로 -20°C에서 1년간 안정적으로 보관 가능합니다.
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ELK Biotechnology RIN2 rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Product name | RIN2 rabbit pAb |
| Applications | WB; ELISA |
| Recommended Dilutions | WB: 1:500–2000, ELISA: 1:5000–20000 |
| Immunogen | Synthesized peptide derived from human protein (AA range: 70–150) |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 98 kD |
| GeneID (Human) | 54453 |
| Human Swiss-Prot No | Q8WYP3 |
| Cellular Localization | Cytoplasm |
| Species Reactivity | Human; Mouse |
| Storage | -20°C, 1 year |
Background
The RAB5 protein is a small GTPase involved in membrane trafficking in the early endocytic pathway. The protein encoded by this gene binds the GTP-bound form of the RAB5 protein preferentially over the GDP-bound form and functions as a guanine nucleotide exchange factor for RAB5. The encoded protein is found primarily as a tetramer in the cytoplasm and does not bind other members of the RAB family. Mutations in this gene cause macrocephaly alopecia cutis laxa and scoliosis (MACS) syndrome, an elastic tissue disorder, as well as the related connective tissue disorder, RIN2 syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2011]
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