ELK Biotechnology AT2B3 rabbit pAb
AT2B3 rabbit polyclonal antibody for WB and ELISA applications. Targets human plasma membrane calcium ATPase isoform 3. High specificity and stability, suitable for calcium transport research. Stored at -20°C for up to 1 year.
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AT2B3 Rabbit Polyclonal Antibody
제품 개요
AT2B3 rabbit pAb는 인간 단백질에서 유래한 합성 펩타이드를 면역원으로 사용한 항체로, 세포막 칼슘 ATPase isoform 3을 인식합니다. 세포 내 칼슘 항상성 연구에 적합합니다.
제품 정보
| 항목 | 내용 |
|---|---|
| Product name | AT2B3 rabbit pAb |
| Applications | WB; ELISA |
| Recommended Dilutions | WB: 1:500–2000, ELISA: 1:5000–20000 |
| Immunogen | Synthesized peptide derived from human protein (AA range: 140–220) |
| Species Reactivity | Human; Rat |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 134 kD |
| GeneID (Human) | 492 |
| Human Swiss-Prot No | Q16720 |
| Cellular Localization | Cell membrane; Multi-pass membrane protein; Cell junction, synapse, presynaptic cell membrane; Localized at parallel fiber terminals |
| Storage | -20°C / 1 year |
Background
The protein encoded by this gene belongs to the family of P-type primary ion transport ATPases characterized by the formation of an aspartyl phosphate intermediate during the reaction cycle. These enzymes remove bivalent calcium ions from eukaryotic cells against very large concentration gradients and play a critical role in intracellular calcium homeostasis. The mammalian plasma membrane calcium ATPase isoforms are encoded by at least four separate genes, and their diversity is further increased by alternative splicing. Expression of different isoforms and splice variants is developmentally, tissue-, and cell type-specific, suggesting functional adaptation to physiological needs. This gene encodes the plasma membrane calcium ATPase isoform 3.
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