ELK Biotechnology NR0B2 rabbit pAb
NR0B2 단백질을 인식하는 토끼 폴리클로날 항체로, WB 및 ELISA에 적합합니다. 인간, 랫드, 마우스 시료에서 반응하며 핵과 세포질에 위치한 단백질 검출에 사용됩니다. 고순도 IgG 형태로 -20°C에서 1년간 보관 가능합니다.
- 판매단위
- pk
카탈로그
2개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다ELK Biotechnology · ELK Biotechnology NR0B2 rabbit pAb
NR0B2 rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Product name | NR0B2 rabbit pAb |
| Applications | WB; ELISA |
| Recommended Dilutions | WB 1:500–2000, ELISA 1:5000–20000 |
| Immunogen | Synthesized peptide derived from human protein (AA range: 30–110) |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 28 kD |
| Gene ID (Human) | 8431 |
| Human Swiss-Prot No. | Q15466 |
| Cellular Localization | Nucleus, Cytoplasm. Colocalizes with NEUROD1 in the nucleus. |
| Species Reactivity | Human; Rat; Mouse |
Background
The protein encoded by this gene is an unusual orphan receptor that contains a putative ligand-binding domain but lacks a conventional DNA-binding domain. It belongs to the nuclear hormone receptor family, a group of transcription factors regulated by small hydrophobic hormones. Some members, including this one, are orphan nuclear receptors with no known ligands. The protein interacts with retinoid and thyroid hormone receptors, inhibiting their ligand-dependent transcriptional activation. It also interacts with estrogen receptors, leading to inhibition of their function. Studies suggest that this protein represses nuclear hormone receptor-mediated transactivation via two mechanisms: competition with coactivators and direct transcriptional repression. (RefSeq, Jul 2008)
ELK Biotechnology 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.