ELK Biotechnology FANCM rabbit pAb
FANCM 단백질을 인식하는 토끼 다클론 항체로 WB 및 ELISA에 적합. 인간, 랫드, 마우스 시료에 반응하며 핵 내 단백질 검출에 유용. 고순도 IgG 형식으로 1 mg/ml 농도, -20°C에서 1년 보관 가능.
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제품명
FANCM rabbit pAb
제품 설명
FANCM 단백질을 인식하는 토끼 다클론 항체로, Western Blot(WB) 및 ELISA 분석에 적합합니다. 인간, 랫드, 마우스 시료에서 반응하며, 핵 내 단백질 검출에 유용합니다.
제품 정보
| 항목 | 내용 |
|---|---|
| Applications | WB; ELISA |
| Recommended Dilutions | WB 1:500–2000, ELISA 1:5000–20000 |
| Immunogen | Synthesized peptide derived from part region of human protein |
| Host Species | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 225 kD |
| Gene ID (Human) | 57697 |
| Human Swiss-Prot No. | Q8IYD8 |
| Cellular Localization | Nucleus |
| Species Reactivity | Human; Rat; Mouse |
Background
The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM, and FANCN (also called PALB2). The previously defined group FANCH is the same as FANCA.
Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair.
The members of the Fanconi anemia complementation group do not share sequence similarity; they are related by their assembly into a common nuclear protein complex.
This gene encodes the protein for complementation group M. Alternative splicing results in multiple transcript variants. (Provided by RefSeq, Apr 2015)
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